Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that thrives in the inflamed environment of the gingival crevice, and is strongly associated with periodontal disease.The host response to P.gingivalis requires TLR2, however P.gingivalis benefits from TLR2-driven Feminine Hygiene Products signaling via activation of PI3K.We studied TL
Mary Magdalene, the Apostola of the Easter Morning: Changes in the Late Medieval Carthusian Office of St Mary Magdalene
The Office of Mary Magdalene is one of the rare offices of Snorkels the Carthusian liturgy that was changed after it had been established as a solemn feast with twelve lessons.In Matins, several chants changed their position or were even replaced by new ones.This article examines the relationship between the earlier and the later Office of St Mary
Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells.
Plasmacytoid Dendritic Cells (pDCs) represent a key immune cell in the defense against viruses.Through pattern recognition receptors (PRRs), these cells detect viral pathogen associated molecular Pediatric Upper Respiratory patterns (PAMPs) and initiate an Interferon (IFN) response.pDCs produce the antiviral IFNs including the well-studied Type I a